Chemical Industry Blog

Triethylene glycol (TEG) , a colorless, odorless, and hygroscopic liquid with the chemical formula C₆H₁₄O₄, is a versatile compound widely used across industries. Its ability to absorb moisture, high boiling point, and low toxicity make it essential in applications from natural gas dehydration to pharmaceutical formulations. However, TEG’s environmental impact and operational challenges present notable limitations. This blog explores TEG’s benefits, drawbacks, and strategies for optimization, providing a comprehensive guide for industry professionals in 2025’s sustainable landscape.

Introduction: TEG’s Role in Modern Industry

TEG is a key member of the polyethylene glycol family, produced through ethylene oxide hydration. Its global market exceeds 175,000 metric tons annually, driven by its unique properties:

High boiling point : 285°C, suitable for high-temperature processes.

Hygroscopicity : Absorbs 5-10% water by weight.

Low toxicity : Oral LD50 &gt;10 g/kg in rats, safer than ethylene glycol.

TEG’s applications span oil and gas, pharmaceuticals, cosmetics, and manufacturing. Despite its advantages, environmental concerns like benzene emissions and operational costs require careful management. This article examines TEG’s role, balancing its benefits against challenges, with data-driven insights.

TEG in the Oil and Gas Industry

The oil and gas sector dominates TEG’s global consumption, accounting for over 60% of its use, primarily in natural gas dehydration to prevent pipeline corrosion and hydrate formation. In glycol dehydration units, TEG’s hygroscopic nature enables it to absorb water vapor efficiently in absorber towers, reducing water content to below 7 lb/MMSCF and meeting stringent pipeline specifications. The “lean” TEG contacts wet gas, stripping moisture, while reboilers regenerate the “rich” TEG to 99% purity at temperatures of 200–230°C. Alongside TEG, calcium chloride (CaCl₂) is sometimes used in auxiliary dehydration steps or upstream pretreatment because of its strong deliquescent properties, enhancing initial moisture removal in challenging reservoir conditions. This combined approach ensures more stable dehydration efficiency before the gas enters TEG contactors. TEG remains the primary medium due to its recyclability—its low vapor pressure (0.01 mmHg at 20°C) minimizes losses, allowing recycling up to 100 times, reducing operational costs by 20–30% compared to alternatives like molecular sieves. Its compatibility with sour gases containing H₂S or CO₂, together with the optional use of CaCl₂ in pretreatment stages, enhances versatility in offshore and shale gas operations where hydrate control is critical for safe and uninterrupted pipeline transport.

Advantages in Dehydration

TEG’s efficiency and recyclability make it a top choice:

High water absorption : Removes 99%+ of water vapor, achieving &lt;7 lb/MMSCF.

Low vapor loss : 0.1-0.5% per cycle, recyclable up to 100 times.

Cost efficiency : Reduces operating costs by 20-30% compared to solid desiccants.

Energy savings : Optimized systems cut energy use by 15% through circulation adjustments.

Environmental edge : Eliminates solid waste, unlike adsorption methods.

In LNG plants, TEG systems cost $0.05-0.10/MSCF, including utilities, making them scalable for high-volume operations. TEG’s ability to handle sour gases and its compatibility with existing infrastructure further enhance its appeal.

Key Metrics :

Absorption capacity : 5-10% water by weight.

Regeneration efficiency : 99% purity post-reboiling.

Cost savings : 25% lower than molecular sieves.

Limitations

TEG’s drawbacks include environmental and operational challenges:

VOC emissions : Absorbs BTEX, emitting 10-20 tons/year per unit.

Energy-intensive regeneration : Requires 200-230°C, consuming 10-15% of plant power.

Degradation : Oxygen exposure forms acids, corroding equipment.

Losses : 5-10% TEG lost in flash tanks.

Mitigation Strategies :

Use inert gas blanketing to reduce degradation by 20%.

Install vapor recovery units to cut emissions by 50%.

Optimize circulation rates to minimize losses and enhance efficiency.

TEG in Pharmaceuticals and Cosmetics

TEG’s biocompatibility and solvent properties make it invaluable in pharmaceuticals as an excipient and in cosmetics as a humectant, with a market growth rate of 5% CAGR through 2030. In pharmaceuticals, TEG enhances drug solubility in syrups and suspensions, improving bioavailability by 15–20%, crucial for effective oral medications. Its low toxicity (LD50 &gt;10 g/kg) ensures safety in formulations. In cosmetics, TEG’s moisture-retaining ability extends product shelf life by 6–12 months, ideal for lotions and creams. Its antimicrobial properties, capable of inactivating 99% of bacteria like Streptococcus , also support its use in sanitizers. Additionally, the incorporation of triazine -based preservatives —widely used for their strong microbial control and chemical stability—further boosts formulation durability, making TEG–triazine systems highly effective for long-lasting personal care and pharmaceutical products. TEG’s non-greasy texture suits sensitive skin applications, and its low volatility ensures consistent aerosol performance, solidifying its role in modern alcohol-free and clean-beauty formulations.

Advantages

TEG enhances product quality and stability:

Solubility enhancement : Improves bioavailability in syrups by 15-20%.

Moisture retention : Extends cosmetic shelf life by 6-12 months.

Antimicrobial action : Inactivates 99% of bacteria like Streptococcus.

Low volatility : Ensures uniform aerosol distribution in sanitizers.

Regulatory approval : CIR-approved for rinse-off cosmetic products.

In pharmaceuticals, TEG stabilizes emulsions in oral suspensions, while in cosmetics, it provides non-greasy hydration for sensitive skin. Its versatility supports clean beauty trends, with demand rising in alcohol-free formulations.

Key Metrics :

Bioavailability boost : 15% higher drug absorption.

Market growth : 5% CAGR in cosmetics.

Bacterial reduction : 99% in sanitizers.

Limitations

Challenges in this sector include:

Dioxane contamination : Risk of 1,4-dioxane (&gt;10 ppm) requires costly purification.

Skin irritation : Draize score 0.5-1 in leave-on products.

Regulatory costs : Testing adds 15% to production expenses.

Mitigation :

Use USP-grade TEG with &lt;1 ppm dioxane.

Limit to rinse-off formulations to avoid irritation.

Implement rigorous quality control to meet FDA and REACH standards.

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TEG as Plasticizers and Solvents in Manufacturing

TEG serves as a plasticizer in vinyl polymers and a solvent in paints, inks, and textiles, enhancing product flexibility and performance. In PVC films, TEG improves durability by 20% compared to phthalates, ensuring long-lasting flexibility. Its high flash point (&gt;150°C) reduces fire risks in manufacturing. As a solvent, TEG ensures even dye dispersion in textiles, improving color consistency. In paints and inks, it enhances flow and stability, supporting high-quality finishes. Its compatibility with polyurethane foams boosts production efficiency, making it a versatile choice across industrial applications. TeamChem supplies high-purity TEG tailored for these applications, ensuring consistent performance, reliable quality control, and technical support for manufacturers seeking optimized formulations .

Advantages

TEG’s properties improve manufacturing processes:

Enhanced flexibility : 20% better durability in PVC films compared to phthalates.

Safety : High flash point (&gt;150°C) reduces fire risks.

Lubricity : Cuts wear in brake fluids by 15%.

Compatibility : Works with polyurethane foams, boosting production efficiency.

In automotive applications, TEG’s use in brake fluids ensures smooth operation under high pressure, reducing wear by 15% and enhancing safety. In textiles, it dissolves dyes evenly, improving color consistency and vibrancy. Its low volatility prevents evaporation, ensuring stable dyeing processes and high-quality fabric finishes across diverse textile applications.

Key Metrics :

Durability increase : 20% in plastics.

Fire safety : Flash point 150°C.

Market share : 10% of plasticizer market.

Limitations

Challenges include:

High viscosity : 40-50 cP slows mixing, adding 10% energy costs.

Explosion risk : TEG dinitrate in propellants is shock-sensitive.

Environmental persistence : High soil mobility in wastewater.

Mitigation :

Use low-viscosity blends to improve mixing efficiency.

Implement strict handling protocols for propellants.

Treat wastewater to prevent soil contamination.

Niche Applications of TEG

TEG’s versatility extends to HVAC, agriculture, and entertainment:

HVAC dehumidification : Absorbs 5-8% moisture in air systems.

Smoke machines : Low-toxicity base for theatrical fog.

Insecticides : Enhances carrier efficacy by 10%.

Air sanitization : Inactivates 99% airborne microbes, ideal for hospitals.

In tobacco and inks, TEG prevents drying, improving print quality and product consistency. Its low odor makes it suitable for consumer-facing products.

Limitations

Foaming : Reduces HVAC efficiency by 10-15%.

Microbial growth : Requires preservatives, adding 5% to costs.

Mitigation :

Add antifoam agents for HVAC systems.

Use sterile storage to prevent microbial contamination.

Environmental and Sustainability Considerations

TEG is 100% biodegradable in 28 days under aerobic conditions, but environmental challenges persist:

Advantages :

Low ecotoxicity: NOEC &gt;100 mg/L for aquatic life.

High recyclability: 90% waste reduction in closed-loop systems.

Limitations :

VOC emissions: 10-20 tons/year per dehydration unit.

Benzene contamination: &gt;0.5 mg/L in waste.

Soil mobility: Risk of groundwater contamination.

Mitigation :

Vapor recovery units reduce emissions by 50%.

Bio-based TEG trials cut carbon footprint by 30%.

Advanced filtration removes benzene from waste streams.

Health and Safety Considerations

TEG’s low toxicity (LD50 &gt;10 g/kg) makes it safer than ethylene glycol, but risks remain:

Advantages :

Minimal CNS effects at &lt;5 g/kg.

Antimicrobial properties for cleanroom applications.

Limitations :

Chronic exposure may cause renal issues.

Flammable gas risk with strong reducers.

Mitigation :

Mandate PPE for workers handling TEG.

Use ventilation systems to minimize aerosol inhalation.

Future Trends and Innovations

TEG demand is projected to grow 4% annually through 2030, driven by LNG and cosmetic sectors:

Innovations :

Nano-enhanced TEG: 20% better absorption.

Bio-TEG: 30% lower carbon footprint.

Hybrid systems with membranes: 25% energy savings.

Sustainability : Zero-emission regenerators using electric heating by 2030.

These advancements ensure TEG’s relevance in a greener future, with bio-based production gaining traction.

Conclusion

TEG’s efficiency, recyclability, and versatility make it a cornerstone across industries. Its ability to dehydrate gas, stabilize formulations, and enhance manufacturing is unmatched, yet emissions, costs, and health risks require careful management. With innovations like bio-TEG and zero-emission systems, industries can leverage TEG sustainably. Professionals should adopt strategic oversight to maximize benefits while minimizing drawbacks.

FAQs

What is the primary use of TEG?

Natural gas dehydration.

Is TEG eco-friendly?

Biodegradable but requires emission controls.

How does TEG compare to DEG?

Lower volatility, better regeneration.

What are TEG’s health risks?

Low toxicity, mild irritation.

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